ChemicalBook > CAS DataBase List > 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

Product Name
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
CAS No.
84468-24-6
Chemical Name
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Synonyms
C-1;IQSP;HA-100;HA-100 HYDROCHLORIDE;HA-100 DIHYDROCHLORIDE;1-(5-ISOQUINOLINESULFONYL)PIPERAZINE;1-(5-isoquinolinylsulfonyl)piperazine;1-(5-isoquinolinylsulfonyl)-piperazin;5-(Piperazin-1-ylsulfonyl)isoquinoline;Isoquinoline,5-(1-piperazinylsulfonyl)-
CBNumber
CB8193285
Molecular Formula
C13H15N3O2S
Formula Weight
277.34
MOL File
84468-24-6.mol
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1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Property

Melting point:
>240°C (dec.)
Boiling point:
497.4±55.0 °C(Predicted)
Density 
1.332±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO, Methanol, Water
form 
Off-white lyophilized solid.
pka
7.66±0.10(Predicted)
color 
Off-White to Pale Yellow
CAS DataBase Reference
84468-24-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
TM0862600
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Tocris
Product number
0543
Product name
C-1
Purity
≥99%(HPLC)
Packaging
10
Price
$163
Updated
2021/12/16
Tocris
Product number
0543
Product name
C-1
Purity
≥99%(HPLC)
Packaging
50
Price
$669
Updated
2021/12/16
Usbiological
Product number
366887
Product name
HA-100 Dihydrochloride
Packaging
25mg
Price
$505
Updated
2021/12/16
Usbiological
Product number
254849
Product name
C-1
Packaging
10mg
Price
$409
Updated
2021/12/16
ApexBio Technology
Product number
B6343
Product name
C-1
Packaging
25mg
Price
$441
Updated
2021/12/16
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1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Crystalline Solid

Uses

Exhibited potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases

Definition

ChEBI: 5-(1-piperazinylsulfonyl)isoquinoline is a member of isoquinolines.

Biological Activity

Inhibitor of protein kinase C. Vasodilator.

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Suppliers

Canada 1 China 59 Germany 2 South Korea 1 Switzerland 3 United Kingdom 2 United States 23 Global 91

84468-24-6, 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDERelated Search:

Histamine dihydrochloride Piperazine 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE (S)-5-(3-Isobutyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride (S)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE 1-(8-CHLORO-5-ISOQUINOLINE-SULFONYL)PIPERAZINE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE (R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride (S) 5-(3-Isopropyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride (S)-5-(3-Benzyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride H-7 DIHYDROCHLORIDE 1-(8-CHLORO-5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

  • 1-(5-isoquinolinylsulfonyl)-piperazin
  • 1-(5-isoquinolinylsulfonyl)piperazine
  • 1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL
  • 1-(5-ISOQUINOLINYLSULFONYL)-PIPERAZINE HYDROCHLORIDE
  • 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE
  • 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
  • C-1
  • HA-100
  • HA-100 DIHYDROCHLORIDE
  • HA-100 HYDROCHLORIDE
  • 1-(5-isoquinolinesulfonyl)piperazine hydrochloride
  • 1-[(Isoquinolin-5-yl)sulfonyl]piperazine
  • IQSP
  • (141543-63-7) 1-(5-isoquinolinesulfonyl)piperazine hydrochloride
  • Isoquinoline,5-(1-piperazinylsulfonyl)-
  • 5-(Piperazin-1-ylsulfonyl)isoquinoline
  • protein,PKC,Rho-associated kinase,ROCK,kinase,PKG,HA100,inhibit,Inhibitor,Myosin,HA 100,MLCK,HA-100,Rho-associated protein kinase,ROK,PKA,Rho-kinase,Protein kinase C,Protein kinase A
  • 84468-24-6
  • C13H17Cl2N3O2S
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Kinase/Phosphatase Biology
  • Protein Kinase A, C and myosin light chain kinase (PKA, PKC and MLCK)
  • Serine/Threonine Kinase Inhibitors
  • Protein Kinase Inhibitors and Activators
  • Protein Kinase